Publications 2006

1. Bachmann M, Kosan C, Xing PX, Montenarh M, Hoffmann I, Möröy T. The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C. Int J Biochem Cell Biol, 38(3): 430-443, 2006

2. Zhang C, Marme A, Wenger T, Gutwein P, Edler L, Rittgen W, Debatin KM, Altevogt P, Mattern J, Herr I. Glucocorticoid-mediated inhibition of chemotherapy in ovarian carcinomas.
Int J Oncol, 28(2): 551-558, 2006

3. Bachmann M, Horn K, Poleganov MA, Paulukat J, Nold M, Pfeilschifter J, Mühl H. Interleukin-18 secretion and Th1-like cytokine responses in human peripheral blood mononuclear cells under the influence of the toll-like receptor-5 ligand flagellin. Cellular Microbiology, 8(2), 289-300, 2006

4. Plesková M, Beck KF, Behrens MH, Huwiler A, Fichtlscherer B, Wingerter O,Brandes RP, Mülsch A, Pfeilschifter J. Nitric oxide down-regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells. FASEB J, 20(1), 139-141, 2006

5. Xin C, Ren S, Eberhardt W, Pfeilschifter J, Huwiler A. The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signaling cascade and upregulate connective tissue growth factor (CTGF) and collagen type IV expression in renal mesangial cells. Br J Pharmacol., 147(2):164-74, 2006

6. Goren I, Linke A, Müller E, Pfeilschifter J, Frank, S. The Suppressor of Cytokine Signaling (SOCS)-3 is upregulated in impaired skin repair: Implications for keratinocyte proliferation. J Invest Dermatol.,126(2): 477-85, 2006

7. Goren I, Müller E, Pfeilschifter J, Frank, S. Severely impaired insulin signaling in chronic wounds of diabetic ob/ob mice: a potential role of TNFalpha. Am J Pathol, 168(3):765-77, 2006

8. Goren I, Kämpfer H, Müller E, Schiefelbein D, Pfeilschifter J, Frank, S. Oncostatin M expression is functionally connected to neutrophils in the early inflammatory phase of skin repair: implications for normal and diabetis-impaired wounds. J Invest Dermatol.,126(3): 628-37, 2006

9. Ludwig RJ, Werner RJ, Winker W, Boehncke WH, Wolter M, Kaufmann R. Chronic venous insufficiency – a potential trigger for localized scleroderma J Eur Acad Dermatol Venereol., 20(1): 96-9, 2006

10. Stoeck A, Keller S, Riedle S, Sanderson MP, Runz S, Lenaour F, Gutwein P, Ludwig A, Rubinstein E, Altevogt P. A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem J, 393(Pt 3): 609-18, 2006

11. Stirnweiss J, Valkova C, Ziesche E, Drube S, Liebmann C. Muscarinic M2 receptors mediate transactivation of EGF receptor through Fyn kinase and without matrix metalloproteases. Cell Signal. 18(8): 1338-49, 2006

12. Stoeck A, Schlich S, Issa J, Gschwend V, Wenger T, Herr I, Marme A, Bourbie S, Altevogt P, and Gutwein P. L1 on ovarian carcinoma cells is a binding partner for Neuropilin-1 on mesothelial cells. Cancer Letters, 239(2): 212-26, 2006

13. Mühl H, Pfeilschifter J. Controlling the cytokine storm by insulin: Glycogen Synthase Kinase-3 as a target in systemic inflammation. Critical Care Medicine, 34(5): 1567-9, 2006

14. Huwiler A, Döll F, Ren S, Klawitter S, Greening A, Römer I, Bubnova S, Reinsberg L, Pfeilschifter J. Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 in a PKC-alpha dependend mechanism. Biochim. Biophys. Acta - Molecular and Cell Biology of Lipids, 1761(3): 367-76, 2006

15. Boost KA, Hofstetter C, Flondor M, Betz C, Homann M, Pfeilschifter J, Mühl H, Zwissler B. Desflurane differentially affects the release of proinflammatory cytokines in plasma and bronchoalveolar fluid of endotoxemic rats. Int J Mol Med, 17(6): 1139-44, 2006

16. Ludwig RJ, Alban S, Bistrian R, Boehncke WH, Henschler R, Kaufmann R, Gille J. The ability of different forms of heparins to suppress P-selectin function in vitro correlates to their inhibitory capacity on blood-borne metastasis in vivo.
Thromb Haemost, 95(3): 535-40, 2006

17. Rubant S, Ludwig RJ, Pfeffer J, Schulze-Johann P, Kaufmann R, Pfeilschifter JM, Boehncke WH, Radeke HH. Eukaryotic expression of the broad-spectrum chemokine receptor antagonist vMIP-II and its effects on T-cell function in vitro and in vivo. Exp Dermatol. 15(8): 634-42, 2006

18. Fritzsche J , Alban S, Ludwig RJ, Rubant S, Boehncke WH, Schumacher G, Bendas G. The influence of various structural parameters of semisynthetic sulfated polysaccharides on the P-selectin inhibition capacity. Biochemical Pharmacology, 72(4): 474-85, 2006

19. Wienrich BG, Oostingh GJ, Ludwig RJ, Enders S, Harms G, Tauber R, Krahn T, Kramer B, Boehncke WH, and Schön MP. reply to "Efomycine M: an inhibitor of selections ?". Nat Med, 12(8); 873-874, 2006

20. Beck S, Beck G, Ostendorf T, Floege J, Lambeau G, Nevalainen T, Radeke HH, Gurrieri S, Haas U, Thorwart B, Pfeilschifter J, Kaszkin M. Upregulation of group IB secreted phospholipase A2 and its M-type receptor in rat anti-Thy-1 glomerulonephritis. Kidney Int. 70: 1251-1260, 2006

21. Huwiler A, Pfeilschifter J. Altering the Sphingosine-1-phosphate/Ceramide Balance: A Promising Approach for Tumor Therapy? Curr Pharmaceut Design, 12(35): 4625-4635, 2006

22. Dequiedt F, Martin M, von Blume J, Vertommen D, Lecomte E, Mari N, Heinen MF, Bachmann M, Twizere JC, Huang C, Rider MH, Piwnica-Worms H, Seufferlein T, Kettmann R. A new role for hPar-1 kinases, EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases. Mol Cell Biol, 26(19); 7086-7102, 2006

23. Hartner A, Schaefer L, Porst M, Cordasic N, Gabriel N, Klanke B, Reinhardt DP, and Hilgers KF. Role of fibrillin-1 for hypertensive and diabetic glomerular disease. Am J Physiol Renal Physiol 290: F1329-F1336, 2006

24. Kurylowicz A, Ramos-Lopez E, Bednarczuk T, and Badenhoop K. Vitamin D-binding protein (DBP) gene polymorphism is associated with Graves`disease and the vitamin D status in a Polish population study. Exp Clin Endocrinol Diabetes, 114(6): 329-325, 2006

25. Ramos-Lopez E, Ghebru S, van Autreve J, Aminkeng F, Herwig J, Seifried E, Seidl C, van der Auwera B, and Badenhoop K. Neither an intronic CA repeat within the CD48 gene nor the HERV-K18 polymorphisms are associated with type 1 diabetes. Tissue Antigens, 68(2): 147-152, 2006

26. Lieb B, Dimitrova K, Kang HS, Braun S, Gebauer W, Martin A, Hanelt B, Saenz SA, Adema CM, and Markl J. Red blood with blue-blood ancestry: intriguing structure of a snail hemoglobin. Proc Natl Acad Sci USA, 103(32): 12011-12016, 2006

27. Huwiler A and Pfeilschifter J. Hypoxia and lipid signaling. Biol. Chem., 387 (10-11): 1321-1328, 2006

28. Ludwig RJ, Alban S, Boehncke WH. Structural requirements of modified glycosaminoglycans to exert polyvalent anti-inflammatory activities
Mini-Rev Med Chem, 6(9): 1009-1023, 2006

29. Rüster B, Gottig S, Ludwig RJ, Bistrian R, Müller S, Seifried E, Gille J, and Henschler R. Mesenchymal stem cells (MSC) display coordinated rolling and adhesion behaviour on endothelial cells. Blood, 108(12): 3938-3944, 2006

30. Ramos-Lopez E, Jansen T, Ivaskevicius V, Kahles H, Klepzig C, Oldenburg J, Badenhoop K. Protection from type 1 diabetes by vitamin D receptor haplotypes. Ann N Y Acad Sci, 1079: 327-334, 2006

31. Daniel C, Radeke HH, Sartory NA, Zuegel U, Steinmeyer A, and Stein J. The new low calcemic vitamin D analogue 22-ene-25-oxa-vitamin D ameliorates Th1-mediated colitis in mice. J Pharmacol Experimental Therapeutics, 319(2): 622-631, 2006

32. Ludwig RJ, Schindewolf M, Utikal J, Lindhoff-Last E, and Boencke WH. Management of cutanenous heparin hypersensitivity reactions. Thromb Haemost, 96(5): 611-617, 2006

33. Buchhaupt M, Meyer B, Kotter P, Entian KD. Genetic evidence for 18S rRNA binding and an Rpr19p assembly function of yeast nucleolar protein Nep1p. Mol Genet Genomics, 276(3): 273-284, 2006

34. Hankeln T, Klawitter S, Kramer M, Burmester T. Molecular characterization of hemoglobin from the honeybee Apis mellifera. J Insect Physiol, 52(7): 701-710, 2006

35. Burmester T, Storf J, Hasenjager A, Klawitter S, Hankeln T. The hemoglobin genes of Drosophila. FEBS J, 273(3): 468-480, 2006

36. Fujinami RS, von Herrath MG, Christen U, Whitton JL. Molecular mimicry, bystander activation, or viral persistence: Infections and autoimmune disease. Clin Microbiol Rev, 19(1): 80-94, 2006

37. Ejrnaes M, von Herrath MG, Christen U. Cure of chronic viral infection and virus-induced type-1 diabetes by neutralizing antibodies. Clin Dev Immunol, 13(2-4): 337-347, 2006

38. Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG. SOCS-1 protects from virally-induced CD8 T-cell mediated type 1 diabetes. J Autoimmun, 27(3), 166-173, 2006

39. von Allmen N, Christen S, Forster U, Gottstein B, Welle M, Muller N. Acute trchinellosis increases susceptibilityto Giardia lamblia infection in the mouse model. Parasitology, 133(Pt2), 139-149, 2006

40. Fink, K, Lang KS, Manjarrez-Orduno N, Junt T, Senn BM, Holdener M, Akira S, Zinkernagel RM, and Hengartner H. Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses. Eur J Immunol, 36(8), 2094-2105, 2006

41. Brück P, Vilches CN, Ramos-Lopez E, Barboza QO, Ancer RJ, and Flores GJP. Expresion del Her2-Neu en el adenocarcinoma ductal de la glandula mamaria: correlacion con parametros istopatologicos y expresion de receptores estrogenicos en pacientes mexicanas. Ginecol Obstet Mex, 74(10), 516-522, 2006


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