Publications 2005

1. Kautz K, Schwarz M, Radeke HH. Interference with MCP-1 gene expression by vector generated triple helix-forming RNA oligonucleotides.
CMLS, Cell Mol Life Sci, 62:001-015, 2005

2. Djordjevic T, Belaiba RS, Bonello S, Pfeilschifter J, Hess J, Görlach A. Human Urotensin II Is a Novel Activator of NADPH Oxidase in Human Pulmonary Artery Smooth Muscle Cells. Arterioscler Thromb Vasc Biol., 25(3): 519-525, 2005

3. Vlachojannis GJ, Scholz-Pedretti K, Fierlbeck W, Geiger H, Pfeilschifter J, Kaszkin M. Enhanced expression of group IIA secreted phospholipase A2 by elevated glucose levels in cytokine-stimulated rat mesangial cells and in kidneys of diabetic rats.
Clin Nephrol, 63 (5): 356-367, 2005

4. Gunia S, Behrens MH, Stosiek P. Mycobacterial spindle cell pseudotumour (MSP) of the nasal septum clinically mimicking Kaposi's sarcoma: A case report. Rhinology, 43(1): 70-71, 2005

5. Bachmann M, Moroy T. The serine/threonine kinase Pim-1. Int J Biochem Cell Biol, 37(4): 726-30, 2005

6. Haas U, Podda M, Behne M, Gurrieri S, Alonso A, Fürstenberger G, Pfeilschifter J, Lambeau G, Gelb MH, Kaszkin M. Characterization and differentiation-dependent regulation of secreted phospholipases A2 in human keratinocytes and healthy and psoriatic human skin. J Invest Dermatol 124: 204 –211, 2005

7. Kämpfer H, Schmidt R, Geisslinger G, Pfeilschifter J, Frank S. Wound inflammation in diabetic ob/ob mice: functional coupling of prostaglandin biosynthesis to cyclooxygenase-1 activity in diabetes-impaired wound healing. Diabetes, 54(5): 1543-1551, 2005

8. Hoth A, Johannisson R, Syed Ali S, Schulze J, Siegers C-P. Cytotoxicity of organotin compounds in different cultured cell lines. Toxicol. Industr. Health, 131-136, 2005

9. Beck KF, Güder G, Schaefer L, Pleskova M, Babelova A, Behrens MH, Mihalik D, Beck M, Schaefer RM, Pfeilschifter, J. Nitric oxide upregulates induction of plateled-derived growth factor receptor a expression in rat renal mesangial cells and in anti-Thy-1 glomerulonephritis. J Am Soc Nephrol, 16(7): 1948-1957, 2005

10. Hofstetter C, Flondor M, Boost KA, Koehler P, Bosmann M, Pfeilschifter J, Zwissler B, Mühl H. A brief exposure to Isoflurane (50 seconds) significantly impacts on plasma cytokine levels in endotoxemic rats. International Immunopharmacology, 5(10): 1519-1522, 2005

11. Eberhardt W, Kilz T, Akool El-Sayed, Müller R, Pfeilschifter J. Dissociated Glucocorticoids equipotently inhibit cytokine- and cAMP-induced matrix degrading proteases in rat mesangial cells. Biochem Pharmacol, 70(3): 433-445. 2005

12. Calderwood JW, Williams JM, Morgan MB, Nash GB, Savage CO. ANCA induces beta2 integrin and CXC chemokine-dependend neutrophil-endothelial cell interactions that mimic those of highly cytokine-activated endothelium. J Leukoc Biol. 77: 33-43, 2005

13. Daniel C, Schlauch T, Zugel U, Steinmeyer A, Radeke HH, Steinhilber D, Stein J. 22-ene-25-oxa-vitamin D: a new vitamin D analogue with profound immunosuppressive capacities. Eur J Clin Invest 35(5): 343-349, 2005

14. Hauser IA, Spiegler S, Kiss E, Gauer S, Sichler O, Scheuermann EH, Ackermann H, Pfeilschifter JM, Geiger H, Grone HJ, Radeke HH. Prediction of acute renal allograft rejection by urinary monokine induced by IFNgamma (MIG). J Am Soc Nephrol. 16(6): 1849-1858, 2005

15. Radeke HH, von Wenckstern H, Stoidtner K, Sauer B, Hammer S, Kleuser B. Overlapping signaling pathways of sphingosine 1-phosphate and TGF-beta in the murine langerhans cell line XS52. J Immunol. 174(5): 2778-2786, 2005

16. Hofstetter C, Flondor M, Hoegl S, Mühl H, Zwissler B. Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat. Crit Care Med, 33(10): 2317-2322, 2005

17. Petry C, Huwiler A, Eberhardt W, Kaszkin M, and Pfeilschifter J. Hypoxia increases group IIA phospholipase A2 expression under inflammatory conditions in rat renal mesangial cells. J Am Soc Nephrol, 16(10): 2897-2905, 2005

18. Christen U, von Herrath MG. Infections and autoimmunity--good or bad? J Immunol. 174(12): 7481-7486, 2005

19. Ejrnaes M, Videbaek N, Christen U, Cooke A, and Michelsen BK, von Herrath M. Different diabetogenic potential of autoaggressive CD8+ clones associated with IFN-gamma-inducible protein 10 (CXC chemokine ligand 10) production but not cytokine expression, cytolytic activity, or homing characteristics. J Immunol. 174(5): 2746-2755, 2005

20. Hintermann E, Yang N, O'Sullivan D, Higgins JM, and Quaranta V. Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes. J Biol Chem. 280(9): 8004-8015, 2005

21. Gutwein P, Stoeck A, Riedle S, Gast D, Runz S, Condon TP, Marme A, Phong MC, Linderkamp O, Skorokhod A, and Altevogt P. Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. Clin Cancer Res. 11(7): 2492-2501, 2005

22. Gast D, Riedle S, Riedle S, Schabath H, Schlich S, Schneider A, Issa Y, Stoeck A, Fogel M, Joumaa S, Wenger T, Herr I, Gutwein P, and Altevogt P. L1 augments cell migration and tumor growth but not beta3 integrin expression in ovarian carcinomas. Int J Cancer 115(4): 658-665, 2005

23. Ludwig RJ, Zollner TM, Santoso S, Hardt K, Gille J, Baatz H, Schulze Johann P, Pfeffer J, Radeke HH, Kaufmann R, Boehncke WH, and Podda M. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. J Invest Dermatol, 125(5): 969-976, 2005

24. Radeke HH, Ludwig RJ, and Boehncke WH. Experimental approaches to lymphocyte migration in dermatology in vitro and in vivo. Experimental Dermatology 14(9): 641-666, 2005

25. Calderwood JW and Radeke HH. Chapter 4: In vitro techniques to investigate lymphocyte extravasation. In: "Lymphocyte homing to the skin” Boehncke WH (Ed.), CRC Press, Boca Raton, FL, USA, 2005

26. Rhode A, Pauza M, Barral AM, Rodrigo E, Oldstone MB, von Herrath MG, Christen U. Islet-specific expression of IP10 (CXCL10) targets lymphocytes to the pancreas and accelerate type 1 diabetes. J Immunol. 175(6): 3516-3524, 2005

27. Hattenbach LO, Beck KF, Pfeilschifter J, Koch F, Ohrloff C, Schacke W. Pigment-Epithelium-Derived Factor is upregulated in photocoagulated human retinal pigment epithelial cells. Ophthalmic Res. 37 (6): 341-346, 2005

28. Akool ES, Doller A, Müller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W. Nitric oxide induces Timp-1 expression by activating the TGFß-Smad signaling pathway. J Biol Chem., 280 (47): 39403-39416, 2005

29. Haase H, Alvarez J, Petzhold D, Doller A, Behlke J, Erdmann J, Hetzer R, Regitz-Zagrosek V, Vassort G, Morano I. Ahnak is critical for cardiac Ca(v)1.2 calcium channel function and its [beta]-adrenergic regulation. FASEB J. 19 (14): 1969-1977, 2005

30. Christen U, von Herrath MG. Viruses as initiators, accelerators or terminators of autoimmunity?- A question of time and location of infection. Autoimmune Liver Disease (Falk Symposium 142), 2005

31. Pfeilschifter J, Beck KF. Chapter 15, pages: 327-340: Nitric oxide and gene expression. In " Nitric oxide cell signaling and gene expression", Cadenas E and Lamas S (Eds.), Taylor and Francis group, Boca Raton, Fl, USA, 2005

32. Ren S, Xin, C, Beck KF, Saleem MA, Mathieson P, Pavenstädt H, Pfeilschifter J, Huwiler A. PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism. Biochim. Biophys. Res. Commun., 338(4): 1818-24, 2005

33. Döll F, Pfeilschifter J, Huwiler A. The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7. Biochim. Biophys. Acta, 1738(1-3): 72-81, 2005

34. Wahab NA, Schaefer L, Weston BS, Yiannikouris O, Wright A, Babelova A, Schaefer R, Mason RM. Glomerular expression of thrombospondin-1., transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli. Diabetologia, 48: 2650-2660, 2005

35. Schaefer L, Babelova A, Kiss E, Hausser HJ, Baliova M, Krzyzankova M, Marsche G, Young MF, Mihalik D, Gotte M, Malle E, Schaefer RM, Grone HJ. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest, 115, 2223-2233, 2005

36. Heeg MH, Koziolek MJ, Vasko R, Schaefer L, Sharma K, Muller GA, Strutz F. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway. Kidney Int, 68(1): 96-109, 2005

37. Seidler DG, Schaefer L, Robenek H, Iozzo RV, Kresse H, Schönherr E. A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival. Biochem Biophys Res Commun, 15, 332(4): 1162-1170, 2005

38. Schönherr E, Sunderkötter C, Iozzo R, Schaefer L. Decorin, a novel player in the insulin-like growth factor system. J Biol Chem, 280(16): 15767-15772, 2005


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