Publications 2004

1. Petry C, Fritz G, Pfeilschifter J, and Huwiler A. Inhibition of Rho modulates cytokine- induced prostaglandin E2 formation in renal mesangial cells. Biochem Biophys Acta1636:0108-118, 2004

2. Chatterjee PK, Patel NSA, Cuzzocrea S, Brown PAJ, Stewart KN, Mota-Filipe H, Britti D, Eberhardt W, Pfeilschifter J, Thiemermann C: The cyclopentenone prostaglandin 15-deoxy-delta12, 14-prostaglandin J2 ameliorates ischemic acute renal failure. Cardiovasculare Research 61:630-643, 2004

3. Kaszkin M, Beck KF, Eberhardt W, and Pfeilschifter J. Unravelling Green Tea's Mechanisms of Action: More than Meets the Eye. Mol Pharmacol 65: 15-17, 2004

4. Hocher B, Schwarz A, Slowinski T, Bachmann S, Pfeilschifter J, Neumayer HH, Bauer C: In-vivo interaction of nitric oxide and endothelin. Journal of Hypertension (22) 111-119, 2004

5. Rodriguez I, Holloschi A, Kaszkin M, Cheng H, Kabsch K, Hafner M, Alonso A: Activation of phospholipase C-gamma1 in human keratinocytes by hyperosmolar shock without enzyme phosphorylation. Arch Dermatol Res 295(11):490-497, 2004

6. Kaszkin M, Beck KF, Koch E, Erdelmeier C, Kusch S, Pfeilschifter J, Loew D: Downregulation of iNOS expression in rat mesangial cells by special extracts of Harpagophytum procumbens derives from harpagoside-dependent and independent effects. Phytomedicine, 11:585-595, 2004

7. Blume C, Sabuda-Widemann D, Pfeilschifter J, Plum J, Schror K, Grabensee B, Beck KF: Cerivastatin inhibits proliferation of interleukin-1beta-induced rat mesangial cells by enhanced formation of nitric oxide. Eur J Pharmacol 485(1-3):1-10, 2004

8. Hellmuth M, Paulukat J, Ninic R, Pfeilschifter J, Mühl H: Nitric oxide differentially regulates pro- and anti-angiogenic markers in DLD-1 colon carcinoma cells. FEBS Lett 563(1-3):98-102, 2004

9. Boissel JP, Ohly D, Bros M, Gödtel-Armbrust U, Förstermann U, Frank S: The neuronal nitric oxide synthase is upregulated in mouse skin repair and in responce to epidermal growth factor in human HaCaT keratinocytes. J Invest Dermatol 123(1):132-139, 2004

10. Zampetaki A, Mitsialis SA, Pfeilschifter J, Kourembanas S: Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kB. FASEB J 18(10):1090-1092, 2004

11. Gunia S, Behrens MH, Stosiek P: A rare course of Whipple`s disease with atypical cardiac manifestation. Acta Pathologica, Microbiologica, et Immunologica Scandinavica 112(3): 222-224, 2004

12. Fichtlescherer S, Kaszkin M, Breuer S, Dimmler S, Zeiher AM. Elevated secretory group II phospholipase A2 serum activity is assiciated with impaired endothelial vasodilator function in patients with coronary artery disease. Clin Sci (Lond) 106: 511-517, 2004

13. Xin C, Ren S, Kleuser B, Shabahang S, Eberhardt W, Radeke H, Schäfer-Korting M, Pfeilschifter J and Huwiler A. Sphingosine-1-phosphate cross-activates the Smad-signaling cascade and mimics TGFb-induced cell responses. J Biol Chem 279(34):35255-35262, 2004

14. Huwiler A, Xin C, Brust AK, Briner VA, Pfeilschifter J. Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells. Biochim Biophys Acta 1636:159-168, 2004

15. Huwiler A, Pfeilschifter J. Erythropoietin is more than just a promoter of erythropoiesis.
J Am Soc Nephrol. 15(8):2240-2241, 2004

16. Mühl, H, Pfeilschifter J. Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention. Eur J Pharmacol 500(1-3): 63-71, 2004

17. Kahlina K, Goren I, Pfeilschifter J, Frank S. p68 dead box RNA helicase expression in
keratinocytes: Regulation, nuclear localisation, and functional connection to proliferation and
VEGF gene expression. J Biol Chem 279(43):44872-44882, 2004

18. Xin C, Ren S, Pfeilschifter J, Huwiler A. Heterologous desensitivation of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells.
Br J Pharmacol, 143(5):581-589, 2004

19. Schäfer L, Ren S, Schäfer RM, Mihalik D, Babelova A, Huwiler A, Pfeilschifter J. Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats.
Biochem Biophys Res Commun, 5;324(1):247-254, 2004

20. Mühl H, Paulukat J, Höfler S, Hellmuth M, Franzen R, Pfeilschifter J. The HIV protease inhibitor Ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells. Br J Pharmacol, 143(7):890-898, 2004

21. Sun M, Kong L, Wang X, Holmes C, Gao Q, Zhang G-R, Pfeilschifter J, Goldstein DS, Geller A. Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter-2 from a helper virus-free HSV-1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease. Human Gene Ther, 15:1177-1196, 2004

22. Bachmann M, Hennemann H, Xing PX, Hoffmann I, Moroy T. The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint.
J Biol Chem 12;279(46):48319-48328, 2004

23. Potapov EV, Ignatenko S, Nasseri BA, Loebe M, Harke C, Bettmann M, Doller A, Regitz-Zagrosek V, Hetzer R. Clinical significance of PlA polymorphism of platelet GP IIb/IIIa receptors during long-term VAD support. Ann Thorac Surg 77(3):869-874, 2004

24. Fähling M, Perlewitz A, Doller A, Thiele BJ. Regulation of collagen prolyl4-hydroxylase and matrix metalloproteinases in fibrosarcoma cells by hypoxia.
Comp Biochem Physiol C Toxicol Pharmacol 139(1-3):119-126, 2004

25. Itoh K, Cheng L, Kamei Y, Fushiki S, Kamiguchi H, Gutwein P, Stoeck A, Arnold B, Altevogt P, Lemmon V. Brain development in mice lacking L1-L1 homophilic adhesion.
J Cell Biol 165(1):145-154, 2004

26. Thiele BJ, Doller A, Kähne T, Pregla R, Hetzer R, Regitz-Zagrosek V. RNA-Binding Proteins Heterogeneous Nuclear Ribonucleoprotein A1, E1, and K Are Involved in Post-Transcriptional Control of Collagen I and III Synthesis. Circ Res 95(11):1058-1066, 2004

27. Kaszkin M, Schneider B, and Loew D. Kasuistik: Ein hochdosierter Harpagophytum- Spezialextrakt als Phytoanalgetikum und -antiphlogistikum zur Remissionserhaltung des Morbus Crohn. Ärztezeitschrift fuer Naturheilverfahren (2):102-106 2004

28. Kaszkin M, Pfeilschifter J, and Loew D. Harpagophytum-Extrakte als sinnvolle Phytoanalgetika/-antiphlogistika? Schweizer Medizinische Zeitschrift für Phytotherapie (4): 4-8, 2004

29. Jiang X, Multhaupt H, Chan E, Schaefer L, Schaefer RM, Couchman JR. Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis. J Histochem Cytochem, 52(12): 1575-1590, 2004

30. Schönherr E, Sunderkötter C, Schaefer L, Thanos S, Grassel S, Oldberg A, Iozzo RV, Young MF, Kresse H. Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J Vasc Res, 41(6): 499-508, 2004

31. Schaefer L, Mihalik D, Babelova A, Krzyzankova M, Grone HJ, Iozzo RV, Young MF, Seidler DG, Lin G, Reinhardt DP, Schaefer RM. Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury. Am J Pathol, 65(2): 383-396, 2004

32. Yung S, Hausser H, Thomas G, Schaefer L, Kresse H, Davies M. Catabolism of newly synthesized decorin in vitro by human peritoneal mesothelial cells. Perit Dial Int, 24(2): 147-155, 2004


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