Publications 2001

1. Schadow A, Scholz K, Lambeau G, Gelb MH, Fürstenberger G, Pfeilschifter J, and Kaszkin M: Characterization of group X phospholipase A2 as the major enzyme secreted by human keratinocytes and its regulation by the phorbol ester TPA. J. Invest. Dermatol. 116, 31-39, 2001

2. Scholz-Pedretti K, Pfeilschifter J, and Kaszkin M: Potentiation of cytokine induction of group IIA phospholipase A2 in rat mesangial cells by ATP and adenosine via the A2A adenosine receptor. Brit. J. Pharmacol. 132, 37-46, 2001

3. Walpen S, Beck KF, Schaefer L, Raslik I, Eberhardt W, Schaefer RM, and Pfeilschifter J: Nitric oxide induces MIP-2 transcription in rat renal mesangial cells and in a rat model of glomerulonephritis. FASEB J. 15, 571-573, 2001

4. Milovic V, Turchanowa L, Khomutov AR, Khomutov RM, Caspary WF, and Stein J: Hydroxylamine-containing inhibitors of polyamine biosynthesis and impairment of colon cancer cell groth. Biochem. Pharmacol. 61, 199-206, 2001

5. Klasen S, Hammermann R, Fuhrmann M, Lindemann D, Beck KF, and Pfeilschifter J & Racké K: Glucocorticoids inhibit lipopolysaccharide-induced up-regulation of arginase in rat alveolar macrophages. Brit. J. Pharmacol. 132, 1349-1357, 2001

6. Manderscheid M, Messmer UK, Franzen R, and Pfeilschifter J: Regulation of IAP expression by nitric oxide and cytokines: relation to apoptosis induction in rat mesangial cells and RAW 264.7 macrophages. J. Am. Soc. Nephrol. 12, 1151-1163, 2001

7. Stallmeyer B, Pfeilschifter J, and Frank S: Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice. Diabetologia 44, 471-479, 2001

8. Kämpfer H, Pfeilschifter J, and Frank S: Expressional regulation of angiopoietin-1 and -2 and the Tie-1 and -2 receptor tyrosine kinases during cutaneous wound healing: a comparative study of normal and impaired repair. Lab. Invest. 81, 361-373, 2001

9. Stallmeyer B, Kämpfer H, Podda M, Kaufmann R, Pfeilschifter J, and Frank S: A novel keratinocyte mitogen: regulation of leptin and its functional receptor in skin repair. J. Invest. Dermatol. 117, 98-105, 2001

10. Kämpfer H, Kolb N, Manderscheid M, Wetzler C, Pfeilschifter J, and Frank S: Macrophage-derived heme-oxygenase 1: expression, regulation, and possible functions in skin repair. Mol. Med. 7, 488-498, 2001

11. Pfeilschifter J, Eberhardt W, and Beck KF: Regulation of gene expression by nitric oxide. Pflügers Arch. Eur. J. Physiol. 442, 479-486, 2001

12. Loew D, Möllerfeld J, Schrödter A, Puttkammer S, and Kaszkin M: Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. Clin. Pharmacol. Ther. 69, 356-364, 2001

13. Messmer UK, Pereda-Fernandez C, Manderscheid M, and Pfeilschifter J: Dexamethasone inhibits TNF-a-induced apoptosis and IAP protein downregulation in MCF-7 cells. Brit. J. Pharmacol. 133, 467-476, 2001

14. Huwiler A, Böddinghaus B, Pautz A, Dorsch S, Franzen R, Briner VA, Brade V, and Pfeilschifter J: Superoxide potently induces ceramide formation in glomerular endothelial cells.Biochem. Biophys. Res. Commun. 284, 404-410, 2001

15. Pfeilschifter J, Eberhardt W, and Huwiler A: Nitric oxide and mechanisms of redox signalling: Matrix and matrix-metabolizing enzymes as prime NO targets. Eur. J. Pharmacol. 429, 279-286, 2001

16. Schwarz M, and Murphy PM: Kaposi’s sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-kB andinduces proinflammatory cytokine and chemokine production via a C-terminal signaling determinant. J Immunol 167, 505-513, 2001

17. Franzen R, Pautz A, Brautigam L, Geisslinger G, Pfeilschifter J, and Huwiler A: Interleukin 1b induces chronic activation and de-novo synthesis of neutral ceramidase in renal mesangial cells. J Biol Chem 276, 35382-35389, 2001

18. Eberhardt W: Differentielle Modulierung der IL-1b vermittelten Expression der Matrixmetalloprotease-9 (MMP-9) durch ROS und NO. Immunologie Aktuell 1, 132-133, 2001

19. Tegeder I, Pfeilschifter J, and Geisslinger G: Cyclooxygenase-independent actions of cyclooxygenase inhibitors. FASEB J. 15, 2057-2072, 2001

20. Beck KF, Walpen S, Eberhardt W, and Pfeilschifter J: Downregulation of integrin-linked kinase mRNA expression by nitric oxide in rat glomerular mesangial cells. Life Sci 69, 2945-2955, 2001

21. Schwarz M, and Radeke HH: Chemokines and Inflammatory Renal Diseases. Kidney Blood Press Res, 24, 409-411, 2001

22. Paulukat J, Bosmann M, Nold M, Garkisch S, Kämpfer H, Frank S, Raedle J, Zeuzem S, Pfeilschifter J, and Mühl H: Expression and release of IL-18 binding protein in response to Interferon-g. J Immunol, 167 (12), 7038-7043, 2001

23. Turchanowa L, Dauletbaev N, Milovic V, and Stein J: Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells.Europ. J Clin Invest, 31, 887-893, 2001

24. Walker G, Pfeilschifter J, Otten U and Kunz D: Proteolytic cleavage of inducible nitric oxide synthase (iNOS) by calpain I. Biochim Biophys Acta 19, 1568: 216-214, 2001

25. Pfeilschifter J and Beck KF Beck: Räumliche und zeitliche Aspekte der Genregulation durch Stickoxid (NO) . NephroNews 2001, 2: 13-15

26. Andreu T, Ebensperger C, Westphal EM, Klenner T, Stewart AF, Westhof A, Müller P, Knaus R, and von Melchner H: Self-deleting suicide vectors (SDSV): selective killing of p53-deficient cancer cells. Cancer Res, 61, 6925-6930, 2001


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