Publications 2000

1. Eberhardt W, Beeg T, Beck KF, Walpen S, Gauer S, Böhles H, and Pfeilschifter J: Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. Kidney Int. 57, 59-69, 2000

2. Walpen S, Beck KF, Eberhardt W, Apel M, Chatterjee PK, Wray G, Thiemermann C, and Pfeilschifter J: Downregulation of SPARC expression is mediated by nitric oxide in rat mesangial cells and during endotoxemia in the rat. J. Am. Soc. Nephrol. 11, 468-476, 2000

3. Huwiler A, Wartmann M, van den Bosch H, and Pfeilschifter J: Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells. Br. J. Pharmacol. 129, 612-618, 2000

4. Frank S, Kämpfer H, Podda M, Kaufmann R, and Pfeilschifter J: Identification of Copper/Zinc Superoxide Dismutase as a Nitric Oxide-regulated Gene in human Keratinocytes (HaCaT): Implications for Keratinocyte Proliferation. Biochem. J. 346, 719-728, 2000

5. Pfeilschifter J, and Huwiler A: Ceramides as key players in cellular stress response. News Physiol. Sci. 15, 11-15, 2000

6. Muhl H, Kämpfer H, Bosmann M, Frank S, Radeke H, and Pfeilschifter J: Interferon-gamma mediates gene expression of IL-18 binding protein in non-leukocytic cells. Biochem. Biophys. Res. Commun. 267, 960-963, 2000

7. Frank S, Kämpfer H, Wetzler C, Stallmeyer B, and Pfeilschifter J: Large induction of the chemotactic cytokine RANTES during wound repair: a regulatory role for nitric oxide in keratinocyte-derived RANTES expression. Biochem J. 347, 265-273, 2000

8. Messmer UK, Winkel G, Briner VA, and Pfeilschifter J: Suppression of apoptosis by glucocorticoids in glomerular endothelial cells: Effects on cytochrome c-release, Bak upregulation, Bcl-xL downregulation and caspase-3-activation. Br. J. Pharmacol. 129, 1673-1683, 2000

9. Aicher A, Hayden-Ledbetter M, Brady WA, Pezzutto A, Richter G, Magaletti D, Buckwalter S, Ledbetter JA, and Clark EA: Characterization of human inducible costimulator ligand expression and function. J. Immunol. 164, 4689-4696, 2000

10. Zacharowski K, Frank S, Otto M, Chatterjee PK, Cuzzocrea S, Hafner G, Pfeilschifter J, and Thiemermann C: Lipoteichoic acid induces delayed protection in the rat heart: a comparison with endotoxin. Arteriosc. Thromb. Vasc. Biol. 20, 1521-1528, 2000

11. Pfeilschifter J: Adhesion Molecules. Schweiz. Rundsch. Med. Prax. 89, 439-442, 2000

12. Scholz K, Eberhardt W, Rupprecht G, Beck KF, Spitzer S, Pfeilschifter J, and Kaszkin M: Inhibition of NFkB-mediated proinflammatory gene expression in rat mesangial cells by the enolized 1,3-dioxane-4,6-dione-5-carboxamide CGP-43182. Brit. J. Pharmacol. 130, 1183-1190, 2000

13. Huwiler A, Kolter T, Pfeilschifter J, and Sandhoff K: Physiology and pathophysiology of sphingolipid metabolism and signaling. Biochem. Biophys. Acta 1485, 63-99, 2000

14. Wetzler C, Kämpfer H, Stallmeyer B, Pfeilschifter J, and Frank S: Large and sustained inductionof chemokines during impaired wound healing in the genetically diabetic mouse: Prolonged persistance of neutrophils and macrophages during the late phase of repair. J. Invest. Dermatol. 115, 245-253, 2000

15. Wetzler C, Kämpfer H, Pfeilschifter J, and Frank S: Keratinocyte-derived chemotactic cytokines: expressional modulation by nitric oxide in vitro and during cutaneous wound repair in vivo. Biochem. Biophys. Res. Commun. 274, 689-696, 2000

16. Frank S, Stallmeyer B, Kämpfer H, Kolb N, and Pfeilschifter J: Leptin enhances wound reepithelialization: Implication for a direct function of leptin in skin repair. J. Clin. Invest. 106, 501-509, 2000

17. Maihofner C, Euchenhofer C, Tegeder I, Beck KF, Pfeilschifter J, and Geisslinger G: Regulation and immunhistochemical localization of nitric oxide synthases and soluble guanylyl cyclase in mouse spinal cord following nociceptive stimulation. Neurosci. Lett. 290, 71-75, 2000

18. Ziegler I, McDonaldo T, Hesslinger C, Pelletier I, and Boyle P: Development of the pteridine pathway in the zebrafish, Danio rerio. J. Biol. Chem. 275, 18926-18932, 2000

19. Muhl H, Chang JY, Huwiler A, Bosmann M, Paulukat J, Ninic R, Nold M, Hellmuth M, and Pfeilschifter J: Nitric oxide augments release of chemokines from monocytic U937 cells: Modulation by antiinflammatory pathways. Free Radical Bio. Med. 29, 969-980, 2000

20. Messmer UK, Briner VA, and Pfeilschifter J: Basic fibroblast growth factor selectively enhances tumor necrosis factor-alpha-induced apoptotic cell death in glomerular endothelial cells: Effects on apoptotic signaling pathways. J. Am. Soc. Nephrol. 11, 2199-2211, 2000

21. Messmer UK, and Pfeilschifter J: New insights into the mechanism for clearance of apoptotic cells. Bio Essays 22, 878-881, 2000

22. Eberhardt W, Huwiler A, Beck KF, Walpen S, and Pfeilschifter J: Amplification of interleukin-1beta-induced MMP-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappaB and AP-1 and involves activation of the MAPK-pathways. J. Immunol. 165, 5788-5797, 2000

23. Huwiler A, Johansen B, Skarstad A, and Pfeilschifter J: Ceramide binds to the CaLB domain of cytosolic phospholipase A2 and faciliates its membrane docking and arachidonic acid release. FASEB J. 10.1096/fj.00-0370fje, 2000

24. Pfeilschifter J: Signalling pathways of nitric oxide (NO). Kidney Blood Press. Res. 23, 159-161, 2000

25. Kämpfer H, Muhl H, Manderscheid M, Kalina U, Kauschat D, Pfeilschifter J, and Frank S: Regulation of IL-18 expression in keratinocytes (HaCaT): Implications for early wound healing. Eur. Cytokine Network 11, 626-633, 2000

26. Kämpfer H, Paulukat J, Muhl H, Wetzler C, Pfeilschifter J, and Frank S: Lack of interferon- gamma production despite the presence of interleukin-18 during cutaneous wound healing. Molecular Medicine 6, 1016-1027, 2000

27. Turchanowa L, Rogozkin VA, Milovic V, Feldkoren BI, Caspary WF, and Stein J: Influence of physical exercise on polyamine synthesis in the rat skeletal muscle. Eur. J. of Clin. Invest. 30, 72-78, 2000

28. Mankel A, Krause K, Genenger M, Kost G and Kothe E: A hydrophobin accumulated in the Hartig' net of ectomycorrhiza formed between Tricholoma terreum and its compatible host tree is missing in an incompatible association. J. of Applied Botany 74, 95-99, 2000

29. Martin U, Winkler ME, Id M, Radeke H, Arseniev L, Takeuchi Y, Simon AR, Patience C, Haverich A and Steinhoff G: Productive infection of primary human endothelial cells by pig endogenous retrovirus (PERV). Xenotransplantation 7, 138-142, 2000

30. Marchand P, Resch K and Radeke HH: Selective inhibition of monocyte chemoattractant protein-1 gene expression in human embryonal kidney cells by specific triple helix-forming oligonucleotides. J. Immunol. 164, 2070-2076, 2000


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